First published on: Can you take calcium citrate with levothyroxine? This question often arises for those who are managing their thyroid health. It’s important to understand the interaction between calcium citrate and levothyroxine, as taking them together can affect the absorption of the medication. Therefore, if you’re considering whether you can take calcium citrate with levothyroxine, it’s advisable to space them apart to ensure optimal effectiveness. Always consult a healthcare professional for personalized advice regarding this combination.