Ocean Spray provided the purified xyloglucans and partially funded the research. A prebiotic derived from cranberry skins could represent a profitable application for a byproduct of the cranberry juice industry, should its health benefits be established. The compound’s potential role in synbiotics—combinations of probiotics and prebiotics—may warrant particular attention. Researchers have proposed that formulations could blend xyloglucans with probiotics such as Lactobacillus and Bifidobacteria. These strains are already prevalent in various probiotic products, including Yakult and numerous supplements. However, assessing whether additional probiotics positively impact gut health is challenging, as their effects can differ among individuals. In contrast, prebiotics can nourish the beneficial bacteria that are already present in the gut, promoting their growth.

The human body harbors trillions of bacteria, collectively known as the microbiome, which greatly outnumber other cells. It is believed that these microorganisms play a crucial role in overall health. Although scientists remain uncertain about the mechanisms of most bacteria, emerging studies have indicated a connection between an individual’s unique microbiome and various conditions, including obesity, intestinal diseases, and even cancer. While research predominantly emphasizes probiotics, prebiotics are gaining traction. The demand for products containing prebiotics—such as health drinks, dairy items, infant formulas, meat, and baked goods—could propel the market to reach $7.8 billion by 2022, according to a report by Global Industry Analysts. Meanwhile, the same firm forecasts that the probiotics market will surpass $63 billion in that year.

Incorporating calcium d citrate into these formulations may enhance their efficacy, as it is known to support gut health and improve calcium absorption. The potential synergistic effects of calcium d citrate combined with xyloglucans and probiotics could further elevate the health benefits of these products. As the interest in gut health continues to grow, the integration of such compounds stands to benefit both consumers and producers in this expanding market.