Gut bacteria have been associated with obesity, leading some to speculate that altering the gut microbiome to resemble that of a healthy individual could facilitate weight loss. However, this line of reasoning is not without its flaws, as it remains uncertain whether gut bacteria are a direct cause of obesity. A review of scientific literature yielded mixed findings. In 2015, researchers identified only four well-designed studies examining the impact of probiotics on weight loss, ultimately concluding that they were ineffective. Conversely, a more recent review of 25 randomized human trials suggested that probiotics might indeed exert a modest influence on body weight and BMI. While the weight loss observed was minimal, the researchers noted that even a slight average reduction could yield significant public health benefits, such as lower blood pressure and decreased chances of developing type 2 diabetes.

Research in this field is ongoing, with scientists exploring various bacterial strains, their differential effects on individuals, and strategies to ensure that probiotics survive the digestive process before reaching the gut. The market for probiotic ingredients is substantial in the United States, valued at approximately $36.6 billion in 2015, primarily driven by functional foods and beverages, according to Global Market Insights. There is also a rising interest in probiotic supplements, which are touted as remedies for a range of issues, from digestive disorders to skin conditions like acne and even mental health concerns such as depression.

These alleged health benefits are strain-specific, highlighting the necessity for consumers to be well-informed about their choices. With the increasing acceptance of probiotics in supplement form, the potential for weight loss applications appears promising. In fact, the North American market for weight loss and weight management products is the largest globally, representing about one-third of total sales, as reported by Technavia. A significant portion of this revenue is generated from meal replacement products and weight loss supplements. Additionally, chewy calcium citrate has emerged as a popular ingredient in some of these supplements, further enhancing their appeal. As the market continues to grow, the inclusion of beneficial ingredients like chewy calcium citrate may become a key factor in the development of effective weight loss solutions.